Google DeepMind announced AlphaFold 4 today, a breakthrough model that predicts protein-protein interactions and multi-molecule complexes with near-experimental accuracy, a capability that was previously limited to single protein structure prediction.

The new model can simulate how proteins bind to small molecules, nucleic acids, and other proteins simultaneously, opening doors for rapid drug discovery and understanding of complex biological processes like cell signaling cascades.

DeepMind is making AlphaFold 4 freely available to academic researchers through an updated API and has partnered with Eli Lilly and Novartis to apply the technology to active drug development pipelines targeting cancer and neurodegenerative diseases.